Products for Research Use Only
RegisterLogin

Muscone

CAT: 0804-HY-N0633-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0633-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Muscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate[1].
CAS Number
541-91-3
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Interleukin Related; NF-κB; NOD-like Receptor (NLR) ; P-glycoprotein; TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/muscone.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1CC(C)CCCCCCCCCCCC1
Molecular Formula
C16H30O
Molecular Weight
238.41
Precautions
H302, H315, H319, H335
References & Citations
[1]Du Y, et al. Muscone improves cardiac function in mice after myocardial infarction by alleviating cardiac macrophage-mediated chronic inflammation through inhibition of NF-κB and NLRP3 inflammasome. Am J Transl Res. 2018 Dec 15;10 (12) :4235-4246.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
IL-1; IL-6; NF-κB; NLRP3; TNFRSF5/CD40

Related Products

CatalogName
HY-P2820-01Phosphoglucomutase, Rabbit muscle
HY-P2726-01Aldolase, Rabbit muscle
HY-P2804-01GAPDH, rabbit muscle
HY-P2734-01Phosphorylase a, rabbit muscle
HY-P10646-01Muscle homing peptide M12
HY-P2918Phosphoglucose Isomerase, Rabbit muscle
HY-P2799Creatine phosphokinase, Rabbit muscle
HY-P2807K-01L-Lactate Dehydrogenase, bovine muscle
HY-P2807I-01L-Lactate Dehydrogenase, rabbit muscle
HY-P2806APyruvate Kinase (PK), Rabbit Muscle

Alternative Products

CatalogName
TRC-M815090-500MGMuscone
RG-M020000-01(±) -Muscone

Popular Products