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KL antibody

CAT: 0710-FNab10867Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10867Size:100 µg
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Background
May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity) .
Synonyms
Klotho|Klotho peptide|KL|KLOT
Gene ID
9365
UniProt
Q9UEF7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Klotho
Target
KL
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
62, 120 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · Q9UEF7

Klotho

KLOT_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UEF7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KL
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.2.1.31
Processing
Precursor
Secondary accessions
Q5VZ95, Q96KV5, Q96KW5, Q9UEI9, Q9Y4F0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

Disease

Disease variant

PTM

Glycoprotein

Molecular function

GlycosidaseHormoneHydrolase

Domain

RepeatSignalTransmembraneTransmembrane helix

Ligand

Vitamin D

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