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EA4

CAT: 0804-HY-131722-04Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-131722-04Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EA4, a derivative of quinone, is an inhibitor for both rPLA and cPLA. EA4 can inhibit rPLA2 with a Ki value of 130 μM. EA4 can be used for the research of hemostasis, thrombosis, and erythropoiesis[1].
CAS Number
389614-94-2
UNSPSC
12352005
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ea4.html
Purity
98.75
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C(C1=CC=C(N(CC)CC)C=C1)=C2Cl)C3=C(N=CC=C3)C2=O
Molecular Formula
C19H17ClN2O2
Molecular Weight
340.80
References & Citations
[1]Shin, Hae Sook et al. Purification and characterization of a cytosolic, 42-kDa and Ca2+-dependent phospholipase A2 from bovine red blood cells: its involvement in Ca2+-dependent release of arachidonic acid from mammalian red blood cells. The Journal of biological chemistry vol. 277,23 (2002) : 21086-94.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

7-Chloro-6-[4-(diethylamino)phenyl]quinoline-5,8-dione
CAS Number389614-94-2
PubChem CID10042917
IUPAC Name7-chloro-6-[4-(diethylamino)phenyl]quinoline-5,8-dione
Molecular FormulaC19H17ClN2O2
Molecular Weight340.8
XLogP4
Topological Polar Surface Area50.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count24
Formal Charge0
Complexity533
SMILES
CCN(CC)C1=CC=C(C=C1)C2=C(C(=O)C3=C(C2=O)C=CC=N3)Cl
InChI
InChI=1S/C19H17ClN2O2/c1-3-22(4-2)13-9-7-12(8-10-13)15-16(20)19(24)17-14(18(15)23)6-5-11-21-17/h5-11H,3-4H2,1-2H3
InChIKey
XAZVKSMDPVMMPP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 7-Chloro-6-[4-(diethylamino)phenyl]quinoline-5,8-dione
CAS: 389614-94-2
CID: 10042917
Formula: C19H17ClN2O2
MW: 340.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight340.8
XLogP34
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass340.0978555
Monoisotopic Mass340.0978555
Topological Polar Surface Area50.3 Ų
Heavy Atom Count24
Formal Charge0
Complexity533
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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