Succinimide

CAT: 0804-HY-41877-02Size: 10 gDry Ice: NoHazardous: No

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CAT#:0804-HY-41877-02Size:10 g

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Description

Succinimide rapidly hydrolyzes into aspartic acid and aspartic acid during the reduction/alkylation process. Succinimide is utilized in the development of antiepileptic agent[1][2].

CAS Number

123-56-8

Product Name Alternative

Pyrrolidine-2,5-dione

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Others

Assay Protocol

https://www.medchemexpress.com/succinimide.html

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1NC(CC1)=O

Molecular Formula

C4H5NO2

Molecular Weight

99.09

Precautions

H302, H315, H319, H335

References & Citations

[1]Chu GC, et al. Accumulation of succinimide in a recombinant monoclonal antibody in mildly acidic buffers under elevated temperatures. Pharm Res. 2007 Jun;24 (6) :1145-56. |[2]Yan B, et al. Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain. J Pharm Sci. 2009 Oct;98 (10) :3509-21.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Chemical Information

Succinimide

Succinimide is a dicarboximide that is pyrrolidine which is substituted by oxo groups at positions 2 and 5. It is a dicarboximide and a pyrrolidinone.

CAS Number	123-56-8
PubChem CID	11439
IUPAC Name	pyrrolidine-2,5-dione
Molecular Formula	C4H5NO2
Molecular Weight	99.09
XLogP	-1
Topological Polar Surface Area	46.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Heavy Atom Count	7
Formal Charge	0
Complexity	105

SMILES

C1CC(=O)NC1=O

InChI

InChI=1S/C4H5NO2/c6-3-1-2-4(7)5-3/h1-2H2,(H,5,6,7)

InChIKey

KZNICNPSHKQLFF-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 123-56-8

CID: 11439

Formula: C4H5NO2

MW: 99.09

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	99.09
XLogP3	-1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	99.032028402
Monoisotopic Mass	99.032028402
Topological Polar Surface Area	46.2 Å²
Heavy Atom Count	7
Formal Charge	0
Complexity	105
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Succinimide

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