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MOG (35-55) (TFA)

CAT: 0804-HY-P1240A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P1240A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MOG (35-55) (MOG (35-55) ) TFA is a minor component of CNS myelin. MOG (35-55) (TFA) has encephalitogenic activity and induces T cell proliferative. MOG (35-55) (TFA) induces Th1 cytokine response as well as relatively high levels of IgG antibodies. MOG (35-55) (TFA) produces a relapsing-remitting neurological disease with extensive plaque-like demyelination. MOG (35-55) (MOG (35-55) ) TFA can be used for experimental autoimmune encephalomyelitis (EAE) modeling[1][2][3].
Product Name Alternative
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (TFA)
UNSPSC
12352209
Target
Endogenous Metabolite
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/myelin-oligodendrocyte-glycoprotein-peptide-35-55-mouse-rat-tfa.html
Purity
99.68
Solubility
DMSO : 2 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL
Smiles
OC(C(F)(F)F)=O.O=C([C@@H](N)CCSC)N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(O)=O)CCCCN)=O)=O)CC(N)=O)=O)CCCNC(N)=N)=O)CC2=CC=C(O)C=C2)=O)CC(C)C)=O)CC3=CNC=N3)=O)C(C)C)=O)C(C)C)=O)CCCNC(N)=N)=O)CO)=O)CC4=CC=CC=C4)=O)CCC1)=O)CO)=O)CCCNC(N)=N)=O)CC5=CC=C(O)C=C5)=O)CC6=CNC7=CC=CC=C67)=O)=O)C(C)C)=O)CCC(O)=O
Molecular Formula
C120H178F3N35O31S
Molecular Weight
2695.97
References & Citations
[1]Rich C, et, al. Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice. Eur J Immunol. 2004 May;34 (5) :1251-61.|[2]Slavin A, et, al. Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein. Autoimmunity. 1998;28 (2) :109-20.|[3]Giralt M, et, al. Active Induction of Experimental Autoimmune Encephalomyelitis (EAE) with MOG35-55 in the Mouse. Methods Mol Biol. 2018;1791:227-232.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported
Citation 01
Acta Physiol. 2023 Jun;238 (2) :e13974.|Adv Sci (Weinh) . 2025 Jan 13:e2409086.|Cell Death Dis. 2022 Sep 2;13 (9) :759.|Int Immunopharmacol. 2022 Apr:105:108566.|Cornell University. 2025.|EMBO Mol Med. 2025 Sep 29.|Front Biosci (Landmark Ed) . 2025 May 23;30 (5) :37838.|Mol Biol Rep. 2025 Nov 15;53 (1) :92.|Research Square Print. September 28th, 2022.

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