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Diazinon

CAT: 0804-HY-B1113-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1113-01Size:100 mg
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Description
Diazinon is an orally active, irreversible AChE inhibitor and insecticide that can be absorbed through the digestive system, skin or respiratory tract. Diazinon inhibits AChE, leading to accumulation of acetylcholine, which in turn overstimulates ACh receptors and affects the nervous system. Diazinon also produces reactive oxygen species (ROS), which induce oxidative stress in various tissues. Diazinon is mainly used in the agricultural field as an insecticide and may have potential effects on human and animal health[1][2][3][4].
CAS Number
333-41-5
Product Name Alternative
Dimpylate
UNSPSC
12352005
Hazard Statement
H301-H350-H410
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Diazinon.html
Purity
99.71
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
S=P(OCC)(OCC)OC1=NC(C(C)C)=NC(C)=C1
Molecular Formula
C12H21N2O3PS
Molecular Weight
304.35
Precautions
P264-P270-P273-P280-P330-P391-P405-P501
References & Citations
[1]Girón-Pérez MI, et al. Diazinon toxicity in hepatic and spleen mononuclear cells is associated to early induction of oxidative stress. Int J Environ Health Res. 2022 Oct;32 (10) :2309-2323.|[2]Zein MA, et al. Toxic effects of combined stressors on Daphnia pulex: Interactions between diazinon, 4-nonylphenol, and wastewater effluent. Environ Toxicol Chem. 2015 May;34 (5) :1145-53.|[3]Shah MD, et al. Diazinon-induced oxidative stress and renal dysfunction in rats. Food Chem Toxicol. 2010 Dec;48 (12) :3345-53.|[4]Neishabouri EZ, et al. Evaluation of immunotoxicity induced by diazinon in C57bl/6 mice. Toxicology. 2004 Mar 15;196 (3) :173-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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