Pyridoxine-d5 (hydrochloride)

Pyridoxine-d5 (hydrochloride)

• CAS Number: 82896-38-6
• UNSPSC Description: Pyridoxine-d5 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride[1]. Pyridoxine hydrochloride (Pyridoxol;Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol;Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway[2].
• Target Antigen: Endogenous Metabolite; Keap1-Nrf2
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease;NF-κB
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Neurological Disease
• Solubility: 10 mM in DMSO
• Smiles: OCC1=C(O)C(C([2H])([2H])[2H])=NC=C1C([2H])([2H])O.Cl
• Molecular Weight: 210.67
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Li C, et al. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. Cell Mol Biol (Noisy-le-grand). 2018 Jul 30;64(10):119-124.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported