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Blarcamesine

CAT: 0804-HY-105296-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-105296-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Blarcamesine is an orally bioavailable Sigma-1 receptor agonist and muscarinic receptor modulator, with anticonvulsant, anti-amnesic, neuroprotective and antidepressant properties. Blarcamesine ameliorates neurologic impairments in a mouse model of Rett syndrome[1].
CAS Number
195615-83-9
UNSPSC
12352005
Target
MAChR; Sigma Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/blarcamesine.html
Purity
99.51
Solubility
DMSO : 116.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CN(C)CC1C(C2=CC=CC=C2)(C3=CC=CC=C3)OCC1
Molecular Formula
C19H23NO
Molecular Weight
281.39
References & Citations
[1]Walter E Kaufmann, et al. ANAVEX®2-73 (Blarcamesine), a Sigma-1 Receptor Agonist, Ameliorates Neurologic Impairments in a Mouse Model of Rett Syndrome. Pharmacol Biochem Behav . 2019 Dec;187:172796.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
Sigma 1 Receptor

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