(2-Chloropyridin-4-yl)methanamine hydrochloride

• UNSPSC Description:

  (2-Chloropyridin-4-yl)methanamine hydrochloride is a selective LOXL2 inhibitor with an IC50 of 126 nM.

• Target Antigen:

  Monoamine Oxidase

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/LOXL2-IN-1_hydrochloride.html

• Purity:

  99.70

• Solubility:

  DMSO : ≥ 33 mg/mL|H2O : ≥ 50 mg/mL

• Smiles:

  [H]Cl.ClC1=NC=CC(CN)=C1

• Molecular Weight:

  179.05

• References & Citations:

  [1]Hutchinson JH, et al. Small Molecule Lysyl Oxidase-like 2 (LOXL2) Inhibitors: The Identification of an Inhibitor Selective for LOXL2 over LOX. ACS Med Chem Lett. 2017 Mar 1;8(4):423-427.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  916210-98-5