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K134

CAT: 0804-HY-U00186-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-U00186-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
K134 is a phosphodiesterase 3 (PDE3) inhibitor. The IC50s of K134 toward PDE3A, PDE3B, PDE5, PDE2 and PDE4 are 0.1, 0.28, 12.1, >300 and >300 μM, respectively.
CAS Number
189362-06-9
Product Name Alternative
OPC33509
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/K134.html
Concentration
10mM
Purity
99.84
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NCCCOC1=CC2=C(NC(C=C2)=O)C=C1)N(C3CC3)[C@H]4[C@H](O)CCCC4
Molecular Formula
C22H29N3O4
Molecular Weight
399.48
References & Citations
[1]Yoshida H, et al. K-134, a phosphodiesterase 3 inhibitor, prevents brain damage by inhibiting thrombus formation in a rat cerebral infarction model. PLoS One. 2012;7 (10) :e46432.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
PDE2; PDE3

Alternative Products

CatalogName
BA8192-10K134