Galangin

• Description :

  Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor. Galangin (Norizalpinin) also shows inhibition of CYP1A1 activity.

• Product Name Alternative :

  Norizalpinin; 3,5,7-Trihydroxyflavone

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Autophagy; Cytochrome P450

• Type :

  Natural Products

• Related Pathways :

  Autophagy; Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Galangin.html

• Purity :

  99.99

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  O=C1C(O)=C(C2=CC=CC=C2)OC3=CC(O)=CC(O)=C13

• Molecular Formula :

  C15H10O5

• Molecular Weight :

  270.24

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Ciolino HP, et al. The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor. Br J Cancer. 1999 Mar;79 (9-10) :1340-6.|[2]Wen M, et al. Galangin induces autophagy through upregulation of p53 in HepG2 cells. Pharmacology. 2012;89 (5-6) :247-55.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  CYP1

• CAS Number :

  [548-83-4]