Usmarapride

• Description :

  Usmarapride (SUVN-D4010) is a potent, selective, orally active and brain penetrant 5-HT4 receptor partial agonist (EC50=44 nM) . Usmarapride (SUVN-D4010) can be used for the research of cognitive deficits associated with Alzheimer's disease[1].

• Product Name Alternative :

  SUVN-D4010

• UNSPSC :

  12352005

• Target :

  5-HT Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/usmarapride.html

• Concentration :

  10mM

• Purity :

  98.0

• Solubility :

  DMSO : 33.33 mg/mL (ultrasonic)

• Smiles :

  CC(N1N=C(C2=NN=C(C3CCN(CCCOC)CC3)O2)C4=C1C=CC=C4)C.O=C(O)C(O)=O

• Molecular Formula :

  C23H31N5O6

• Molecular Weight :

  473.52

• References & Citations :

  [1]Nirogi, Ramakrishna; Mohammed, Abdul Rasheed; Yarlgadda, Suresh; Ravella, Srinivasa Rao; Shinde, Anil Karbhari; Kambhampati, Ramasastri; Roayalley, Praveen Kumar; Jayarajan, Pradeep; Bhyrapuneni, Gopinadh; Patnala, Sriramachandra Murthy; et al. Preparation of heteroaryl compounds as 5-HT4 receptor ligands.WO2013042135A1

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• Isoform :

  Apolipoprotein D

• CAS Number :

  [1428862-33-2]