Aloperine

CAT: 0804-HY-13516-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No
CAT#:0804-HY-13516-01Size:10 mM - 1 mL
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Description
Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties[1]. Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China[2]. Aloperine induces apoptosis and autophagy in HL-60 cells[1].
CAS Number
[56293-29-9]
UNSPSC
12352005
Hazard Statement
H302
Target
Apoptosis; Autophagy; Filovirus; HIV
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Autophagy
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/aloperine.html
Concentration
10mM
Purity
99.80
Solubility
DMSO : 5.56 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
[H][C@]1(C2)[C@](CCCC3)([H])N3C[C@]2([H])[C@@]4([H])C(CCCN4)=C1
Molecular Formula
C15H24N2
Molecular Weight
232.37
Precautions
H302
References & Citations
[1]Lin Z, et al. In vitro anti-tumour activities of quinolizidine alkaloids derived from Sophora flavescens Ait. Basic Clin Pharmacol Toxicol. 2011 May;108 (5) :304-9.|[2]Yuan XY, et al. Effects and mechanisms of aloperine on 2, 4-dinitrofluorobenzene-induced allergic contact dermatitis in BALB/c mice. Eur J Pharmacol. 2010 Mar 10;629 (1-3) :147-52.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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