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EGFR Antibody (CF488)

CAT: 0013-GTR18722702Size: 0.5 mLDry Ice: NoHazardous: No
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CAT#:0013-GTR18722702Size:0.5 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR Antibody (CF488)
Product Name Alternative
Erbb1; ERBB1; Errp; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor Tyrosine Protein Kinase; ErbB1; Urogastrone; wa2; Wa5
UniProt
P00533
Reactivity
Human
Immunogen
Recombinant extracellular domain of human EGFR protein
Target
EGFR
Clonality
Monoclonal
Clone
GFR450
Conjugation
CF488
Field of Research
Cell Biology
Purification
Protein A
Concentration
Purified Ab conjugated to CF488
Dilution
Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood) ; Immunofluorescence (1:50-1:100) ; Optimal dilution for a specific application should be determined.
Form
Antibody purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules. Prepared in 10mM PBS with 0.05% rAlbumin and 0.05% azide. Contact us if you require this Ab in a different format.
Molecular Weight
~170kDa (wild type) and ~145kDa (vIII variant)
Storage Conditions
Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Notes
For research use only.
Applications Notes
Positive Control: A431 cells, Breast or Bladder cancer.
Tested Applications
FC, IF
Host or Source
Mouse
Preservative
Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules. Prepared in 10mM PBS with 0.05% rAlbumin and 0.05% azide. Contact us if you require this Ab in a different format.
Isotype
IgG2a
Entrez
1956

UniProtKB · P00533

Epidermal growth factor receptor

EGFR_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P00533
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EGFR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
O00688, O00732, P06268, Q14225, Q68GS5, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneEndoplasmic reticulumEndosomeGolgi apparatusMembraneNucleusSecreted

Molecular function

Developmental proteinHost cell receptor for virus entryKinaseReceptorTransferaseTyrosine-protein kinase

Disease

Disease variantProto-oncogene

PTM

Disulfide bondGlycoproteinHydroxylationIsopeptide bondLipoproteinMethylationPalmitatePhosphoproteinUbl conjugation

Biological process

Host-virus interaction

Domain

RepeatSignalTransmembraneTransmembrane helix

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