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CCT129202

CAT: 0804-HY-12049-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12049-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CCT129202 is an aurora kinase inhibitor with IC50s of 42, 198, and 227 nM for aurora A, B and C, respectively.
CAS Number
942947-93-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Aurora Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/CCT129202.html
Purity
99.62
Solubility
DMSO : 1 mg/mL (ultrasonic)
Smiles
CN(C1=CC=C(C2=NC3=C(C(Cl)=CN=C3N2)N4CCN(CC4)CC(NC5=NC=CS5)=O)C=C1)C
Molecular Formula
C23H25ClN8OS
Molecular Weight
497.02
Precautions
H302, H315, H319, H335
References & Citations
[1]Chan F, et al. Mechanism of action of the Aurora kinase inhibitor CCT129202 and in vivo quantification of biological activity. Mol Cancer Ther. 2007 Dec;6 (12 Pt 1) :3147-57.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Aurora A; Aurora B; Aurora C

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