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Frunevetmab

CAT: 0804-HY-P99627-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99627-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats[1][2].
CAS Number
1708936-80-4
Product Name Alternative
NV-02; PG110; ABT-110
UNSPSC
12352203
Target
Trk Receptor
Type
Inhibitory Antibodies
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/frunevetmab.html
Purity
95.00
Solubility
10 mM in DMSO
Smiles
[Frunevetmab]
Molecular Weight
(148 kDa)
References & Citations
[1]Margaret E Gruen, et al. Frunevetmab, a felinized anti-nerve growth factor monoclonal antibody, for the treatment of pain from osteoarthritis in cats. J Vet Intern Med. 2021 Nov;35 (6) :2752-2762. |[2]Margaret E Gruen, et al. Frunevetmab, a felinized anti-nerve growth factor monoclonal antibody, for the treatment of pain from osteoarthritis in cats. J Vet Intern Med. 2021 Nov;35 (6) :2752-2762. |[3]D P Gearing, et al. In Vitro and In Vivo Characterization of a Fully Felinized Therapeutic Anti-Nerve Growth Factor Monoclonal Antibody for the Treatment of Pain in Cats. J Vet Intern Med. 2016 Jul;30 (4) :1129-37.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported

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