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KBH-A42

CAT: 0804-HY-126211Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-126211Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KBH-A42 is a novel histone deacetylase (HDAC) inhibitor with significant anti-inflammatory properties. KBH-A42 against TNF-α and NO production with IC50 values of 1.10 and 2.71 µM, respectively, in the LPS-induced murine macrophage RAW 264.7 cells[1].
CAS Number
798543-50-7
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/kbh-a42.html
Smiles
O=C(CCC1=CCCN(C1=O)CCCC2=CC=CC=C2)NO
Molecular Formula
C17H22N2O3
Molecular Weight
302.37
References & Citations
[1]Yongseok Choi, et al. Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model. Experimental & Molecular Medicine. 2008, 40, 574-581.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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