Products for Research Use Only

XRCC6 Antibody (CF488)

CAT: 0013-GTR18722510Size: 0.5 mLDry Ice: NoHazardous: No
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CAT#:0013-GTR18722510Size:0.5 mL
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Description
XRCC6 Antibody (CF488)
Product Name Alternative
70kDa / 80kDa subunit of Ku antigen; CTC box-binding factor 75kDa subunit; CTC75; CTCBF; G22P1; Lupus Ku autoantigen protein p70; ML8; Thyroid autoantigen 70kD (Ku antigen) ; Thyroid-lupus autoantigen (TLAA) ; X-ray repair cross-complementing protein 6 (XRCC6) ; ATP-dependent DNA helicase II 80kDa subunit; CTC box-binding factor 85kDa subunit; CTC85; CTCBF; KARP1; KUB2; Lupus Ku autoantigen protein p86; Nuclear factor IV (NFIV) ; X-ray repair cross-complementing protein 5 (XRCC5)
UniProt
P12956
Reactivity
Human
Immunogen
Nuclear extract of human HL-60 cells
Target
XRCC6
Clonality
Monoclonal
Clone
KU729
Conjugation
CF488
Field of Research
Epigenetics & Chromatin
Purification
Protein G
Concentration
Purified Ab conjugated to CF488
Dilution
Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood) ; Immunofluorescence (1:50-1:100) ; Optimal dilution for a specific application should be determined.
Form
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
Molecular Weight
70kDa & 80kDa
Storage Conditions
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Notes
For research use only.
Applications Notes
Positive Control: Human cancer K562, HL-60, HEp-2 or HeLa cells.
Tested Applications
FC, IF
Host or Source
Mouse
Preservative
Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules. Prepared in 10mM PBS with 0.05% rAlbumin and 0.05% azide. Contact us if you require this Ab in a different format.
Isotype
IgG1
Entrez
7520, 2547

UniProtKB · P12956

DNA repair protein Ku70

XRCC6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P12956
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
XRCC6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
4.2.99.18, 5.6.2.4
Processing
—
Secondary accessions
B1AHC8, Q6FG89, Q9UCQ2, Q9UCQ3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationADP-ribosylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-bindingHelicaseHydrolaseIsomeraseLyaseMultifunctional enzyme

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

ChromosomeCytoplasmNucleus

Biological process

DNA damageDNA recombinationDNA repairHost-virus interactionImmunityInnate immunityTranscriptionTranscription regulation

Disease

Systemic lupus erythematosus

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