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AGS-16C3F Antibody

CAT: 0013-GTR18712316-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18712316-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AGS-16C3F is an antibody-drug conjugate (ADC) targeting ENPP3 (also known as CD203c) . This product consists of a humanized IgG1 monoclonal antibody against ENPP3 conjugated to the microtubule inhibitor monomethyl auristatin F (MMAF) via a non-cleavable linker. AGS-16C3F functions by specifically binding to ENPP3 on the surface of tumor cells, undergoing internalization, and releasing MMAF intracellularly to induce cell cycle arrest and apoptosis. It exhibits potent anti-tumor and anti-proliferative activity in ENPP3-expressing metastatic renal cell carcinoma (mRCC) and systemic mastocytosis.
Target
Others
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Metabolism Research
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.

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Alternative Products

CatalogName
F1889-50Anti-ENPP3/CD203c Antibody (Ags-16C3F)
HY-P990315-01Anti-ENPP3/CD203c Antibody (AGS-16C3F antibody)
E24CHB344Anti-ENPP3 / CD203c Reference Antibody (Ags-16C3F)
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NBP3-28126CL1Human Monoclonal ENPP-3/CD203c Antibody (Ags-16C3F) [CoraFluor 1]
NBP3-28126-1mgCHO Monoclonal ENPP-3/CD203c Antibody (Ags-16C3F) - Humanized - (Dry Ice)
NBP3-28126JF669Human Monoclonal ENPP-3/CD203c Antibody (Ags-16C3F) [Janelia Fluor 669]
NBP3-28126JF635Human Monoclonal ENPP-3/CD203c Antibody (Ags-16C3F) [Janelia Fluor 635]
NBP3-28126JF525Human Monoclonal ENPP-3/CD203c Antibody (Ags-16C3F) [Janelia Fluor 525]
NBP3-28126JF585Human Monoclonal ENPP-3/CD203c Antibody (Ags-16C3F) [Janelia Fluor 585]

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