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PTIO

CAT: 0804-HY-131898-02Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-131898-02Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PTIO is a specific scavenger of NO and redox mediator. PTIO reacts with •NO to form the corresponding imino nitroxides and •NO2. PTIO enhances organic contaminants oxidation by permanganate[1][2][3].
CAS Number
18390-00-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents; NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ptio.html
Purity
99.80
Solubility
DMSO : 166.67 mg/mL (ultrasonic)
Smiles
[O]N1C(C)(C)C(C)(C)[N+]([O-])=C1C2=CC=CC=C2
Molecular Formula
C13H17N2O2
Molecular Weight
233.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Goldstein S, et al. Reactions of PTIO and carboxy-PTIO with *NO, *NO2, and O2-*. J Biol Chem. 2003;278 (51) :50949-50955.|[2]Xia JL , et al. Putrescine regulates nitric oxide accumulation in Ganoderma lucidum partly by influencing cellular glutamine levels under heat stress. Microbiol Res. 2020;239:126521.|[3]Zhao L, et al. PTIO as a redox mediator to enhance organic contaminants oxidation by permanganate. Water Res. 2023 Oct 1;244:120500.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide

partial structure given in first source; endothelium-derived relaxing factor antagonist

CAS Number18390-00-6
PubChem CID2733513
Molecular FormulaC13H17N2O2
Molecular Weight233.29
XLogP1.2
Topological Polar Surface Area33
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count1
Heavy Atom Count17
Formal Charge0
Complexity316
SMILES
CC1(C([N+](=C(N1[O])C2=CC=CC=C2)[O-])(C)C)C
InChI
InChI=1S/C13H17N2O2/c1-12(2)13(3,4)15(17)11(14(12)16)10-8-6-5-7-9-10/h5-9H,1-4H3
InChIKey
DYUUGILMVYJEHY-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide
CAS: 18390-00-6
CID: 2733513
Formula: C13H17N2O2
MW: 233.29
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight233.29
XLogP31.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count1
Exact Mass233.129002789
Monoisotopic Mass233.129002789
Topological Polar Surface Area33 Ų
Heavy Atom Count17
Formal Charge0
Complexity316
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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