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DFNA5 Antibody (N-term)

CAT: 0013-GTR18704804-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18704804-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Purified Rabbit Polyclonal Antibody (Pab)
Product Name Alternative
Non-syndromic hearing impairment protein 5, Inversely correlated with estrogen receptor expression 1, ICERE-1, DFNA5, ICERE1
UniProt
O60443
Reactivity
Human
Immunogen
This DFNA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-87 amino acids from the N-terminal region of human DFNA5. Antigen Region: 59-87 aa.
Target
GSDME {ECO:0000303|PubMed:28459430, ECO:0000312|HGNC:HGNC:2810}
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution
WB - 1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Molecular Weight
54555 Da
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
NCBI Accession Number
NP_001120926.1, NP_004394.1, NP_001120925.1
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · O60443

Gasdermin-E

GSDME_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60443
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GSDME
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A4D156, B2RAX9, B3KT05, O14590, Q08AQ8, Q9UBV3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCytoplasmMembrane

Disease

DeafnessNon-syndromic deafnessTumor suppressor

PTM

Isopeptide bondLipoproteinPalmitateUbl conjugation

Biological process

Necrosis

Domain

TransmembraneTransmembrane beta strand

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