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5M038

CAT: 0804-HY-122204Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-122204Size:1 Each
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Description
5M038 is an inhibitor of HIV envelope-mediated fusion with potent inhibitory activity against gp41-mediated membrane fusion. 5M038 prevents the formation of the gp41 post-fusion conformation and inhibits envelope-mediated membrane fusion in cell-cell fusion and viral infectivity assays. 5M038 has shown broad fusion inhibition in tests against multiple HIV-1 subtypes, including M and T strains. 5M038 targets a highly conserved hydrophobic pocket and binds to the gp41 trimer, thereby exerting its inhibitory effect[1].
CAS Number
338962-32-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/5m038.html
Smiles
FC(F)(F)C1=C2C=CC3=NN=C(N3C2=NC(C(F)(F)F)=C1)C4=CC=CC=C4
Molecular Formula
C17H8F6N4
Molecular Weight
382.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
MBS57761275M038

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