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2-Deoxy-D-galactose

CAT: 0804-HY-131892-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-131892-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2-Deoxy-D-galactose is a glucose analog. 2-Deoxy-D-galactose inhibits glycolysis to inhibits tumor growth. 2-Deoxy-D-galactose is a substance interfering with the fucosylation of glycomacromolecules and impairing memory consolidation in various learning tasks. 2-Deoxy-d-galactose hinders glycoprotein fucosylation in vivo[1].
CAS Number
1949-89-9
UNSPSC
12352211
Hazard Statement
H302, H315, H317, H319, H335, H372, H411
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-deoxy-d-galactose.html
Purity
99.90
Solubility
H2O : 175 mg/mL (ultrasonic) |Methanol : 125 mg/mL (ultrasonic)
Smiles
O=CC[C@H]([C@H]([C@@H](CO)O)O)O
Molecular Formula
C6H12O5
Molecular Weight
164.16
Precautions
H302, H315, H317, H319, H335, H372, H411
References & Citations
[1]Keppler DO, et al. The trapping of uridine phosphates by D-galactosamine. D-glucosamine, and 2-deoxy-D-galactose. A study on the mechanism of galactosamine hepatitis. Eur J Biochem. 1970 Dec;17 (2) :246-53.|[2]Krug M, et al. The amnesic substance 2-deoxy-D-galactose suppresses the maintenance of hippocampal LTP. Brain Res. 1991 Feb 1;540 (1-2) :237-42. |[3]Lorenzini CG, et al. 2-Deoxy-D-galactose effects on passive avoidance memorization in the rat. Neurobiol Learn Mem. 1997 Nov;68 (3) :317-24.|[4]Smith DF, Keppler DO. 2-Deoxy-D-galactose metabolism in ascites hepatoma cells results in phosphate trapping and glycolysis inhibition. Eur J Biochem. 1977 Feb 15;73 (1) :83-92.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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