2-Deoxy-D-galactose

• UNSPSC Description:

  2-Deoxy-D-galactose is a glucose analog. 2-Deoxy-D-galactose inhibits glycolysis to inhibits tumor growth. 2-Deoxy-D-galactose is a substance interfering with the fucosylation of glycomacromolecules and impairing memory consolidation in various learning tasks. 2-Deoxy-d-galactose hinders glycoprotein fucosylation in vivo[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Cancer; Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/2-deoxy-d-galactose.html

• Purity:

  99.90

• Solubility:

  H2O : 250 mg/mL (ultrasonic)|Methanol : 125 mg/mL (ultrasonic)

• Smiles:

  O=CC[C@H]([C@H]([C@@H](CO)O)O)O

• Molecular Weight:

  164.16

• References & Citations:

  [1]Keppler DO, et al. The trapping of uridine phosphates by D-galactosamine. D-glucosamine, and 2-deoxy-D-galactose. A study on the mechanism of galactosamine hepatitis. Eur J Biochem. 1970 Dec;17(2):246-53.|[2]Krug M, et al. The amnesic substance 2-deoxy-D-galactose suppresses the maintenance of hippocampal LTP. Brain Res. 1991 Feb 1;540(1-2):237-42. |[3]Lorenzini CG, et al. 2-Deoxy-D-galactose effects on passive avoidance memorization in the rat. Neurobiol Learn Mem. 1997 Nov;68(3):317-24.|[4]Smith DF, Keppler DO. 2-Deoxy-D-galactose metabolism in ascites hepatoma cells results in phosphate trapping and glycolysis inhibition. Eur J Biochem. 1977 Feb 15;73(1):83-92.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  1949-89-9