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N-Nitrosomorpholine

CAT: 0804-HY-131123-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0804-HY-131123-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
N-Nitrosomorpholine is a photosensitive nitrosamine that is carcinogenic and can be used to construct animal cancer models[1].
CAS Number
59-89-2
UNSPSC
12352005
Hazard Statement
H301, H351
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-nitrosomorpholine.html
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=NN1CCOCC1
Molecular Formula
C4H8N2O2
Molecular Weight
116.12
Precautions
H301, H351
References & Citations
[1]K D Brunnemann, et al. N-Nitrosomorpholine and Other Volatile N-nitrosamines in Snuff Tobacco. Carcinogenesis. 1982;3 (6) :693-6.|[2]Kobusch AB, et al. Tumor-promoting activity and cytotoxicity of 3,4,3',4'-tetrachlorobiphenyl on N-nitrosomorpholine-induced murine liver foci. J Cancer Res Clin Oncol. 1989;115 (3) :247-52.|[3]Enzmann H, et al. Elevation of glucose-6-phosphate in early stages of hepatocarcinogenesis induced in rats by N-nitrosomorpholine. Horm Metab Res. 1988 Feb;20 (2) :128-9.|[4]Weber E, et al. Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by continuous oral exposure to N-nitrosomorpholine. Carcinogenesis. 1994 Jun;15 (6) :1235-42.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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