Recombinant Human MHC Class I Polypeptide-Related Sequence A (MICA), Partial

• Gene Name:

  [MICA]

• NCBI Gene ID:

  100507436

• Storage Conditions:

  Store at -20 degree C. For extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.

• Specificity:

  Widely expressed with the exception of the central nervous system where it is absent. Expressed predominantly in gastric epithelium and also in monocytes, keratinocytes, endothelial cells, fibroblasts and in the outer layer of Hassal's corpuscles within the medulla of normal thymus. In skin, expressed mainly in the keratin layers, basal cells, ducts and follicles. Also expressed in many, but not all, epithelial tumors of lung, breast, kidney, ovary, prostate and colon. In thyomas, overexpressed in cortical and medullar epithelial cells. Tumors expressing MICA display increased levels of gamma delta T-cells.

• Other Gene Names:

  [MICA; MICA; MIC-A; PERB11.1; MIC-A]

• Short Name:

  [MHC Class I Polypeptide-Related Sequence A (MICA)]

• Other Product Names:

  [MHC class I polypeptide-related sequence A; MHC class I polypeptide-related sequence A; MHC class I polypeptide-related sequence A; MHC class I polypeptide-related sequence A]

• NCBI GI Number:

  74740024

• NCBI Accession Number:

  Q29983.1

• Uniprot Accession Number:

  Q29983

• CAS Number:

  9000-83-3