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CYM50260

CAT: 0804-HY-108494-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-108494-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CYM50260 is a potent and exquisitely selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonist with an EC50 of 45 nM. CYM50260 displays no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R[1].
CAS Number
1355026-60-6
UNSPSC
12352005
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cym50260.html
Purity
99.70
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
FCC1=CC=C(OCCOC2=CC=C(Cl)C=C2Cl)C(Cl)=N1
Molecular Formula
C14H11Cl3FNO2
Molecular Weight
350.60
References & Citations
[1]Guerrero M, et al. Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P₄-R) agonists. Bioorg Med Chem Lett. 2012 Jan 1;22 (1) :537-42.|[2]Onuma T, et al. Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor. Thromb Res. 2017 Aug;156:91-100.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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