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NS004

CAT: 0804-HY-117931-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-117931-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NS004 is a potassium (BK) channel activator that increases Iberiotoxin or Tetraethylammonium (HY-B1793) -sensitive whole-cell efflux currents. NS004 also significantly increased the activity of individual GH3 cell BK channels and rat brain BK channels reorganized into planar lipid bilayers, causing an increase in channel mean open time, a decrease in intermittent time, and an increase in channel voltage/calcium sensitivity[1].
CAS Number
141797-92-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ns004.html
Purity
99.67
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1N(C2=CC=C(C=C2N1)C(F)(F)F)C3=CC(Cl)=CC=C3O
Molecular Formula
C14H8ClF3N2O2
Molecular Weight
328.67
Precautions
H302, H315, H319, H335
References & Citations
[1]Opening of Large-Conductance Calcium-Activated Potassium Channels by the Substituted Benzimidazolone NS004
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
T28195-01NS004

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