Closed-HMRG

• Description:

  Closed-HMRG is HMRG with closed spirocyclic structure. Ac-HMRG, an acetylated derivative of Hydroxymethyl rhodamine green, exists as a closed spirocyclic structure in aqueous solution at physiological pH, whereas HMRG itself takes an open nonspirocyclic structure. Ac-HMRG is colorless and nonfluorescent and HMRG is strongly fluorescent[1].

• UNSPSC:

  12171500

• Target:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/closed-hmrg.html

• Smiles:

  NC1=CC=C2C(OC3=CC(N)=CC=C3C24OCC5=C4C=CC=C5)=C1

• Molecular Formula:

  C20H16N2O2

• Molecular Weight:

  316.35

• References & Citations:

  [1]Masayo Sakabe, et al. Rational design of highly sensitive fluorescence probes for protease and glycosidase based on precisely controlled spirocyclization. J Am Chem Soc. 2013 Jan 9;135 (1) :409-14.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  [7449-51-6]