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SP4206

CAT: 0804-HY-119424-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119424-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SP4206 is an IL-2/IL-2Rα interaction inhibitor. SP4206 binds with high affinity (Kd=70 nM) to IL-2 and blocks binding to its natural receptor IL-2Rα (Kd=10 nM) [1].
CAS Number
515846-21-6
Product Name Alternative
AM152 (sodium), AM152
UNSPSC
12352005
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sp4206.html
Purity
96.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(COC2=CC=C(C3=NN(C)C(C4CCN(C(CNC([C@@H](CC(C)C)NC(N)=N)=O)=O)CC4)=C3)C(Cl)=C2Cl)O1)O
Molecular Formula
C30H37Cl2N7O6
Molecular Weight
662.56
References & Citations
[1]Thanos CD, et al. Hot-spot mimicry of a cytokine receptor by a small molecule. Proc Natl Acad Sci U S A. 2006 Oct 17;103 (42) :15422-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-2

Alternative Products

CatalogName
GTR19204741-01SP4206

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