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HMGCR Rabbit Polyclonal Antibody

CAT: 0013-GTR18685523-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18685523-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-HMGCR Polyclonal Antibodyis a rabbit polyclonal antibody detecting 3-hydroxy-3-methylglutaryl-coenzyme A reductase in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Cricetulus griseus. Highlights Affinity Purified: Minimal background and high purity for reliable results. Multi-Application: Validated across multiple applications. Multi-Species: Cross-reactive for translational research.
Product Name Alternative
3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMGCR, HMG-CoA reductase
UniProt
P04035
Reactivity
Bovine, Golden Hamster, Hamster, Human, Mouse, Porcine, Rabbit, Rat
Immunogen
E. coli - derived recombinant Human HMGCR (Glu441-Asn875) .
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Metabolism Research
Purification
Purified by antigen affinity column.
Concentration
Lot dependent
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, IHC, WB
Host or Source
Rabbit
Preservative
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Isotype
IgG

UniProtKB · P04035

3-hydroxy-3-methylglutaryl-coenzyme A reductase

HMDH_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04035
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HMGCR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
HMG-CoA reductase
EC number
1.1.1.34
Processing
—
Secondary accessions
B7Z3Y9, Q8N190
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cholesterol biosynthesisCholesterol metabolismLipid biosynthesisLipid metabolismSteroid biosynthesisSteroid metabolismSterol biosynthesisSterol metabolism

Disease

Disease variantLimb-girdle muscular dystrophy

Cellular component

Endoplasmic reticulumMembranePeroxisome

PTM

GlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Ligand

NADP

Molecular function

Oxidoreductase

Domain

TransmembraneTransmembrane helix

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