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NSP3/PL-PRO Rabbit Polyclonal Antibody

CAT: 0013-GTR18679507-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18679507-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-NSP3/PL-PRO Polyclonal Antibodyis a rabbit polyclonal antibody detecting Non-structural protein 3 in ELISA, IHC, WB. Highlights Affinity Purified: Minimal background and high purity for reliable results. Multi-Application: Validated across multiple applications.
Product Name Alternative
Non-structural protein 3, nsp3, PL2-PRO, Papain-like protease, Papain-like proteinase, PL-PRO, Replicase polyprotein 1ab, pp1ab, ORF1ab polyprotein
UniProt
P0DTD1
Reactivity
Virus
Immunogen
E. coli - derived recombinant SARS-CoV-2 NSP3/PL-PRO (Glu1024-Gln1198) .
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen affinity column.
Concentration
Lot dependent
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, IHC, WB
Host or Source
Rabbit
Preservative
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Isotype
IgG

UniProtKB · P0DTD1

Replicase polyprotein 1ab

R1AB_SARS2 · Severe acute respiratory syndrome coronavirus 2

View on UniProt ↗
Primary accession
P0DTD1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
rep
Protein existence
1: Evidence at protein level
Organism
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
Taxonomy ID
2697049
Alternative names
pp1ab
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureReference proteome

Biological process

Activation of host autophagy by virusDecay of host mRNAs by virusEukaryotic host gene expression shutoff by virusEukaryotic host translation shutoff by virusHost gene expression shutoff by virusHost mRNA suppression by virusHost-virus interactionInhibition of host innate immune response by virusInhibition of host interferon signaling pathway by virusInhibition of host IRF3 by virusInhibition of host ISG15 by virusInhibition of host NF-kappa-B by virusInhibition of host RLR pathway by virusInhibition of host TBK1 by virusInhibition of host TLR pathway by virusInterferon antiviral system evasionModulation of host ubiquitin pathway by viral deubiquitinaseModulation of host ubiquitin pathway by virusUbl conjugation pathwayViral immunoevasionViral RNA replication

Ligand

ATP-bindingMetal-bindingNucleotide-bindingZinc

PTM

Disulfide bondIsopeptide bondUbl conjugation

Molecular function

EndonucleaseExonucleaseHelicaseHydrolaseLyaseMethyltransferaseNucleaseNucleotidyltransferaseProteaseRNA-bindingRNA-directed RNA polymeraseThiol proteaseTransferase

Cellular component

Host cytoplasmHost endoplasmic reticulumHost endosomeHost Golgi apparatusHost membraneHost nucleusMembrane

Domain

Leucine-rich repeatRepeatTransmembraneTransmembrane helixZinc-finger

Coding sequence diversity

Ribosomal frameshifting

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