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Pendimethalin

CAT: 0804-HY-B0862-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0862-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pendimethalin is an orally active herbicide that controls annual grasses and certain broadleaf weeds. Pendimethalin induces Apoptotic cell death through activating ER stress-mediated mitochondrial dysfunction in human umbilical vein endothelial cells[1][2][3][4].
CAS Number
40487-42-1
UNSPSC
12352005
Hazard Statement
H302, H317, H400, H410
Target
Apoptosis; Bcl-2 Family; Caspase; SOD
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pendimethalin.html
Purity
99.88
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=[N+](C1=C(NC(CC)CC)C([N+]([O-])=O)=C(C)C(C)=C1)[O-]
Molecular Formula
C13H19N3O4
Molecular Weight
281.31
Precautions
H302, H317, H400, H410
References & Citations
[1]Martin Kočárek, et al. Effect of adjuvant on pendimethalin and dimethenamid-P behaviour in soil. J Hazard Mater. 2018 Jul 15;354:266-274.|[2]Lee HS, et al. Pendimethalin induces apoptotic cell death through activating ER stress-mediated mitochondrial dysfunction in human umbilical vein endothelial cells. Food Chem Toxicol. 2022 Oct;168:113370.|[3]Ansari SM, et al. Pendimethalin induces oxidative stress, DNA damage, and mitochondrial dysfunction to trigger apoptosis in human lymphocytes and rat bone-marrow cells. Histochem Cell Biol. 2018 Feb;149 (2) :127-141. |[4]Ahmad MI, et al. Pendimethalin-induced oxidative stress, DNA damage and activation of anti-inflammatory and apoptotic markers in male rats. Sci Rep. 2018 Nov 20;8 (1) :17139.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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