L-Asparagine-13C4,15N2

L-Asparagine-13C4,15N2

• CAS Number: 781596-75-6
• UNSPSC Description: L-Asparagine-13C4,15N2 ((-)-Asparagine-13C4,15N2) is the 13C and 15N-labeled L-Aspartic acid. L-Aspartic acid is an amino acid, shown to be a suitable pro-agent for colon-specific drug delivery[1][2][3].
• Target Antigen: Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/l-asparagine-13c4-15n2.html
• Solubility: 10 mM in DMSO
• Smiles: [15NH2][13C]([13CH2][13C@H]([15NH2])[13C](O)=O)=O
• Molecular Weight: 138.08
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. J Neurochem. 1999 Sep;73(3):1206-11. |[3]Leopold CS, et al. In vivo pharmacokinetic study for the assessment of poly(L-aspartic acid) as a drug carrier for colon-specific drug delivery. J Pharmacokinet Biopharm. 1995 Aug;23(4):397-406.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported