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AC260584

CAT: 0804-HY-100336-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-100336-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AC260584 is an M1 muscarinic receptor allosteric agonist with a pEC50 of 7.6.
CAS Number
560083-42-3
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/AC260584.html
Concentration
10mM
Purity
99.48
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C1COC2=CC(F)=CC=C2N1CCCN3CCC(CCCC)CC3
Molecular Formula
C20H29FN2O2
Molecular Weight
348.45
References & Citations
[1]Bradley SR, et al. AC260584, an orally bioavailable M (1) muscarinic receptor allosteric agonist, improves cognitive performance in an animal model. Neuropharmacology. 2010 Feb;58 (2) :365-73.|[2]Li Z, et al. AC260584 (4-[3- (4-butylpiperidin-1-yl) -propyl]-7-fluoro-4H-benzo[1,4]oxazin-3-one), a selective muscarinic M1 receptor agonist, increases acetylcholine and dopamine release in rat medial prefrontal cortex and hippocampus. Eur J Pharmacol. 2007 Oct 31;572 (2-3) :129-37.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAChR1

Alternative Products

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GTR19204103-01AC260584
A12264-5AC260584 5mg
A12264-100AC260584 100mg
A12264-10AC260584 10mg
A12264-50AC260584 50mg
A12264-25AC260584 25mg
A12264-1AC260584 1mg
A12264-10mM-DAC260584 10mM * 1mL in DMSO

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