Torbafylline

CAT: 0804-HY-160864-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-160864-01Size:1 mg

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Description

Torbafylline is a PDE inhibitor. Torbafylline mitigates protein breakdown in rat skeletal muscle following burns by activating the PDE4/cAMP/EPAC/PI3K/Akt signaling pathway. Torbafylline suppresses the increased ubiquitin-proteasome-dependent protein degradation observed in the skeletal muscles of rats susceptible to cancer and sepsis[1].

CAS Number

105102-21-4

Product Name Alternative

HWA 448

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/torbafylline.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(N(C)C(N1CCCCC(C)(C)O)=O)N=CN2COCC

Molecular Formula

C16H26N4O4

Molecular Weight

338.40

References & Citations

[1]Okyayuz-Baklouti I. The effects of torbafylline on blood flow, pO2 and function of rat ischaemic skeletal muscle. Eur J Pharmacol. 1989 Jul 4;166 (1) :75-86.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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