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AH3960

CAT: 0804-HY-15103-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15103-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AH3960 (compound 16c) is an antagonist of androgen receptor. AH3960 binds wild as well as T877 mutant type androgen receptors. AH3960 selectively inhibits T877 with an IC50 value of 0.82 μM. AH3960 also serves as an agonist of parathyroid hormone receptor-1 (PTHR1) [1][2].
CAS Number
862907-48-0
UNSPSC
12352005
Target
Androgen Receptor; PTHR
Type
Reference compound
Related Pathways
GPCR/G Protein; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ah3960.html
Purity
99.92
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1/C(C(N(CCCC)C(N1CCCC)=O)=O)=C(N)\N
Molecular Formula
C13H22N4O3
Molecular Weight
282.34
References & Citations
[1]Yamamoto S, et al. Design, synthesis, and biological evaluation of 4-arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as novel androgen receptor antagonists. Bioorg Med Chem. 2012 Apr 1;20 (7) :2338-52. |[2]Carter PH, et al. Actions of the small molecule ligands SW106 and AH-3960 on the type-1 parathyroid hormone receptor. Mol Endocrinol. 2015 Feb;29 (2) :307-21.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
BA9193-1AH3960

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