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VU6036720

CAT: 0804-HY-148304Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-148304Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VU6036720 is a potent and specific in vitro inhibitor of Kir4.1/5.1. VU6036720 can inhibit Kir4.1/5.1 channels with an IC50 value of 0.24 μM. VU6036720 can be used for the research of brain and kidney[1].
CAS Number
3026597-12-3
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu6036720.html
Purity
99.88
Solubility
DMSO : 75 mg/mL (ultrasonic)
Smiles
C[C@H]1CN(CCN1CCNS(=O)(C2=CC(Cl)=C(C=C2)F)=O)C3=C(C#N)C=CC=C3
Molecular Formula
C20H22ClFN4O2S
Molecular Weight
436.93
References & Citations
[1]Samantha J McClenahan, et al. VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels. Mol Pharmacol. 2022 May;101 (5) :357-370.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported