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Cefaclor

CAT: 0804-HY-B0198-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0198-01Size:500 mg
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Description
Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3) . Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections[1][2][3][4].
CAS Number
53994-73-3
UNSPSC
12352005
Hazard Statement
H317, H334
Target
5-HT Receptor; Antibiotic; Bacterial; Penicillin-binding protein (PBP)
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Cefaclor.html
Purity
99.61
Solubility
DMSO : 18.5 mg/mL (ultrasonic; warming) |H2O : 3.85 mg/mL (ultrasonic)
Smiles
O=C(C(N12)=C(Cl)CS[C@]2([H])[C@H](NC([C@H](N)C3=CC=CC=C3)=O)C1=O)O
Molecular Formula
C15H14ClN3O4S
Molecular Weight
367.81
Precautions
H317, H334
References & Citations
[1]Joo MK, et al. Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice. Sci Rep. 2023 Sep 19;13 (1) :15529. |[2]Li M, et al. Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters. Drug Metab Dispos. 2006 Apr;34 (4) :547-55. |[3]Yoo HS, et al. Immunologic evaluation of immediate hypersensitivity to cefaclor. Yonsei Med J. 2014 Nov;55 (6) :1473-83. |[4]Neu HC, et al. Cefaclor: in vitro spectrum of activity and beta-lactamase stability. Antimicrob Agents Chemother. 1978 Apr;13 (4) :584-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
MUC4; β-lactam

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CatalogName
MBS384472-01Cefaclor

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