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VE-Statin/EGFL7

CAT: 0209-M30-100Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0209-M30-100Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFL7 is an ∼ 30 kDa secreted protein that contain an Emilin-like (EMI) domain (a multimerization motif), and 2 epidermal growth factor (EGF) domains, one of which binds calcium. Based on these domains, it has been hypothesized that EGFL7 may self-assemble like extracellular matrix (ECM) proteins and, thus, could incorporate into ECM. EGFL7 has been reported to stimulate cell adhesion as well as motility in a manner similar to ECM proteins. EGFL7 has been shown to be primarily expressed by developing ECs but also by primordial germ cells and some central nervous system neurons. Interestingly, EGFL7 expression markedly decreases in ECs in postnatal life, but can be strongly up-regulated after various tissue injuries that lead to increased angiogenic responses.
Synonyms
Egfl7; EGF-like domain 7; Zneu1; VE-statin
NCBI Gene ID
353156
UniProt
Q9QXT5
Accession Number
NP_942018.2
Accession Number mRNA
NM_198725.2
Chromosomal Location
2; 2 B
Reactivity
Mouse
Cross Reactivity
Mouse
Label
His-Tag
Sequence
YRPSRRVCTVGISGGSISETFVQRVYQPYLTTCDGHRACSTYRTIYRTAYRRSPGVTPARPRYACCPGWKRTSGLPGACGAAICQPPCGNGGSCIRPGHCRCPVGWQGDTCQTDVDECSTGEASCPQRCVNTVGSYWCQGWEGQSPSADGTRCLSKEGPSPVAPNPTAGVDSMAREEVYRLQARVDVLEQKLQLVLAPLHSLASRSTEHGLQDPGSLLAHSFQQLDRIDSLSEQVSFLEEHLGSCSCKKDLHHHHHHHHHHHH
Applications
WB
Assay Protocol
The lyophilized mouse EGFL7 should be reconstituted in water to a concentration of not lower than 50µg/ml.
Purity
> 95% by SDS-PAGE
Bioactivity
Testing under progress.
Length
263
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Molecular Weight
28.8 kDa
Storage Conditions
Lyophilized samples are stable for greater than six months at -20°C to -70°C. Reconstituted EGFL7 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles!
Host or Source
Insect cells