Rabbit Anti-Mouse VEGFR-2/Flk-1 (Peptide) , soluble Polyclonal Antibody

Rabbit Anti-Mouse VEGFR-2/Flk-1 (Peptide) , soluble Polyclonal Antibody

• Description: The antibody recognizes solely the endogenous soluble form of mouse vascular endothelial growth factor receptor 2, alos known as CD309, VEGFR2, KDR, protein tyrosine kinase receptor flk-1, and fetal liver kinase-1. The endogenous soluble mouse esFlk-1 generated by alternative splicing consists of the first 6 Ig-like loops followed by the unique C-terminal end: GMEASLGDRIAMP. Flk-1 is a member of the tyrosine protein kinase family, sub-family CSF-1/PDGF, that contains a single pass transmembrane receptor with a protein kinase domain and seven immunoglobulin-like domains in the extracellular region. Flk-1 is expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle; other tissues express at lower levels. Flk-1 is a receptor for VEGF-A or fully processed VEGF-C; ligand binding plays a key role in vascular development and vascular permeability.
• Synonyms: soluble vascular endothelial growth factor receptor-2 ; soluble Kdr; soluble Ly73; soluble Flk-1; sVEGFR2; sVEGF receptor 2; soluble kinase insert domain protein receptor
• CAS Number: 9007-83-4
• NCBI Gene ID: 16542
• UniProt: P35918
• Accession Number: ACJ66293.1
• Accession Number mRNA: EU884114
• Gene Location: 5 C3.3; 5 42.0 cM
• Host: Rabbit
• Origin Species: Mouse
• Species Reactivity: Mouse
• Target Antigen: Peptide: GMEASLGDRIAMP
• Clone: Rabbit IgG
• Validated Applications: WB
• Purification Method: Protein A purified
• Detection Range: Western Blot: use at 1-5 µg/ml.
• Form: Lyophilized
• Buffer: PBS
• Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
• Shipping Conditions: Room Temperature
• Storage Conditions: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.