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TROP-2

CAT: 0209-103-M497Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-103-M497Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Human TROP-2, also called tumor associated calcium signal transducer 2 (TACSTD2), gp50 and T16, is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It is related to EpCAM, also called TROP-1, gp40 and KSA. A study of these two genes suggests that TROP-2 was generated through the retropositioning of the EpCAM gene. TROP-2 and EpCAM share approximately 49% amino acid sequence identity and approximately 67% similarity. Mature human and mouse TROP-2 share 80% amino acid identity.
Synonyms
Tpm2; Tpm-2; Trop-2
NCBI Gene ID
22004
UniProt
Q8BGV3
Accession Number
NP_064431.2
Accession Number mRNA
NM_020047.3
Chromosomal Location
4 B1; 4
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Mouse recombinant protein TROP-2
Clone
(#25D13)
Applications
WB
Purification Method
Protein A/G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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