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TROP-2

CAT: 0209-101-M691Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M691Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Human TROP-2, also called tumor associated calcium signal transducer 2 (TACSTD2), gp50 and T16, is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It is related to EpCAM, also called TROP-1, gp40 and KSA. A study of these two genes suggests that TROP-2 was generated through the retropositioning of the EpCAM gene. TROP-2 and EpCAM share approximately 49% amino acid sequence identity and approximately 67% similarity. Mature human and mouse TROP-2 share 80% amino acid identity.
Synonyms
TACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1
NCBI Gene ID
4070
UniProt
P09758
Accession Number
NP_002344
Accession Number mRNA
NM_002353
Chromosomal Location
1p32
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant TROP-2
Clone
(#49D6)
Applications
WB, FC
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2A

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