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TMEFF1

CAT: 0209-101-M650Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M650Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transmembrane Protein with EGF-like and two Follistatin-like domains 1 (TMEFF1) also known as tomoregulin-1 is a type I transmembrane glycoprotein. TMEFF1 contains two follistatin modules and an EGF domain in its extracellular domain, a transmembrane domain and a short cytoplasmic tail. The extracellular domain of TMEFF1 can be released as a soluble protein. TMEFF1 is predominantly expressed in brain, but is downregulated in brain neoplasms. TMEFF1 selectively regulates nodal but not activin signaling through direct binding to the nodal co-receptor, Cripto.
Synonyms
TMEFF1; TR-1; H7365; C9orf2; CT120.1
NCBI Gene ID
8577
UniProt
Q8IYR6
Accession Number
NP_003683.2
Accession Number mRNA
NM_003692.4
Chromosomal Location
9q31
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
EC domain of human TMEFF1 (also called Tomoregulin-1)
Clone
(#7S12)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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