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TL-1A

CAT: 0209-102-P253Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-102-P253Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TL1A is a type II transmembrane protein belonging to the TNF superfamily and has been designated TNF superfamily member 15 (TNFSF15) . TL1A is predominantly expressed in endothelial cells and its expression is inducible by TNF-alpha and IL-1alpha. TL1A binds with high affinity to death receptor 3 (DR3), now known as TNFRSF25. Depending on the cell context, ligation of DR3 by TL1A can trigger one of two signaling pathways, activation of the transcription factor NF-kB, or activation of caspases and apoptosis.
Synonyms
TNFSF15; TL1; TL1A; VEGI; VEGI192A
NCBI Gene ID
9966
UniProt
O95150
Accession Number
NP_005109
Accession Number mRNA
NM_005118
Chromosomal Location
9q32
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human TL-1A
Clone
Rabbit IgG
Applications
ELISA, WB
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized from PBS
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Rabbit

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