Rabbit Anti-Mouse TIE-1 Polyclonal Antibody

Rabbit Anti-Mouse TIE-1 Polyclonal Antibody

• Description: TIE-1 (tyrosine kinase with Ig and EGF homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis.
• Synonyms: Tie1; TIE; tie-1; D430008P04Rik
• CAS Number: 9007-83-4
• NCBI Gene ID: 21846
• UniProt: Q06806
• Accession Number: NP_035717.2
• Accession Number mRNA: NM_011587.2
• Gene Location: 4 D2.1; 4 50.0 cM
• Host: Rabbit
• Origin Species: Mouse
• Species Reactivity: Mouse
• Target Antigen: Recombinant Mouse sTIE-1 (RT Cat# S01-M42)
• Clone: Rabbit IgG
• Validated Applications: WB
• Purification Method: Protein A purified
• Detection Range: Western Blot: use at 2-5 µg/ml.
• Form: Lyophilized
• Buffer: PBS
• Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
• Shipping Conditions: Room Temperature
• Storage Conditions: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.