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TFPI

CAT: 0209-101-M834Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M834Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tissue factor pathway inhibitor (or TFPI) is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa) . While Xa is inhibited, the Xa-TFPI complex can subsequently also inhibit the FVIIa-tissue factor complex. TFPI contributes significantly to the inhibition of Xa in vivo, despite being present at concentrations of only 2.5 nM. The gene for TFPI is located on chromosome 2q31-q32.1, and has nine exons which span 70 kb. A similar gene, termed TFPI2, has been identified on chromosome 7, at locus 7q21.3; in addition to TFPI activity, its product also has retinal pigment epithelial cell growth-promoting properties.
Synonyms
Convertin; EPI; Extrinsic pathway inhibitor; LACI; Lipoprotein-associated coagulation inhibitor; TFPI; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) ; tissue factor pathway inhibitor
NCBI Gene ID
7035
UniProt
P10646
Accession Number
NP_00131670.1
Accession Number mRNA
NM_001329241.1
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant Human TFPI
Clone
(#19G38)
Applications
E
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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