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SRY

CAT: 0209-105-PA02Size: 200 µgDry Ice: NoHazardous: No
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CAT#:0209-105-PA02Size:200 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The „Sex determining region of Y-Gen” (SRY), known as SRY gene, is coding for a transkription factor (TDF for Testis-determining factor) . It belongs to the protein family of DNA binding-proteins. The SRY gene is beside other genes used for the determination of the sex in human as well as other mammals. Most mammals have for this purpose a further gene, UBE1. In humans SRY is normally located on the short arm of the Y chromosome. Accordingly, people who possess this chromosome with the corresponding gene, normally have a male phenotype. It does not matter how many copies of the X chromosome are present, even people with a multiple X chromosome (Klinefelter's syndrome) have this. The protein encoded by the gene Testis-determining factor controls the development of male sex.
Synonyms
Sex-determining region Y protein; Testis-determining factor
NCBI Gene ID
280931
UniProt
Q03255
Accession Number
NP_001014407.1
Accession Number mRNA
NM_001014385.1
Reactivity
Anti-Bovine
Cross Reactivity
Bovine
Target Antigen
Recombinant bovine SRY (RT #B30-001)
Clone
Rabbit IgG
Applications
WB
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
Western Blot: Use 1-5 µg/ml
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
Host or Source
Rabbit

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