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SRY

CAT: 0209-B30-001Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0209-B30-001Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The „Sex determining region of Y-Gen” (SRY), known as SRY gene, is coding for a transkription factor (TDF for Testis-determining factor) . It belongs to the protein family of DNA binding-proteins. The SRY gene is beside other genes used for the determination of the sex in human as well as other mammals. Most mammals have for this purpose a further gene, UBE1. In humans SRY is normally located on the short arm of the Y chromosome. Accordingly, people who possess this chromosome with the corresponding gene, normally have a male phenotype. It does not matter how many copies of the X chromosome are present, even people with a multiple X chromosome (Klinefelter's syndrome) have this. The protein encoded by the gene Testis-determining factor controls the development of male sex
Synonyms
Sex-determining region Y protein; Testis-determining factor
NCBI Gene ID
280931
UniProt
Q03255
Accession Number
NP_001014407.1
Accession Number mRNA
NM_001014385.1
Reactivity
Bovine
Cross Reactivity
Bovine
Sequence
MFRVLNDDVYSPAVVQQQTTLAFRKDSSLCTDSHSANDQCERGEHVRESSQDHVKRPMNAFIVWSRERRRKVALENPKMKNSDISKQLGYEWKRLTDAEKRPFFEEAQRLLAIHRDKYPGYKYRPRRRAKRPQKSLPADSSILCNPMHVETLHPFTYRDGCAKTTYSQMESQLSRSQSVIITNSLLQKEHHSSWTSLGHNKVTLATRISADFPCNKSLEPGLSCAYFQYLE
Assay Protocol
Centrifuge vial prior to opening. Bovine SRY should be reconstituted in PBS to a concentration of 0.1 mg/ml. This solution can be diluted in water or other buffered solutions.
Purity
> 90% by SDS-PAGE
Bioactivity
Data not available.
Length
231
Form
Lyophilized
Buffer
Water
Reconstitution
PBS
Molecular Weight
26.8 kDa
Storage Conditions
The lyophilized powder although stable at room temperature for 3 weeks, is best stored desiccated at -20°C. Reconstituted bo SRY should be stored in working aliquots at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .
Host or Source
E. coli
N Terminal Sequence
MFRVLN

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