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Sonic Hedgehog (N-terminal)

CAT: 0209-101-M833Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M833Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Members of the Hedgehog (Hh) family are highly conserved proteins which are widely represented throughout the animal kingdom. The three known mammalian Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh) are structurally related and share a high degree of amino-acid sequence identity (e.g., Shh and Ihh are 93% identical) . The biologically active form of Hh molecules is obtained by autocatalytic cleavage of their precursor proteins and corresponds to approximately the N-terminal one half of the precursor molecule. Although Hh proteins have unique expression patterns and distinct biological roles within their respective regions of secretion, they use the same signaling pathway and can substitute for each other in experimental systems. Recombinant E. coli derived Human Sonic HedgeHog is a 20.0 kDa protein consisting of 176 amino acid residues, including an N-terminal Ile-Val-Ile sequence substituted for the natural occurring chemically modified Cys residue.
Synonyms
Sonic Hedgehog
NCBI Gene ID
6469
UniProt
Q15465
Accession Number
NP_000184.1
Accession Number mRNA
NM_000193.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant Human Sonic Hedgehog
Clone
(#2G19)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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Alternative Products

CatalogName
MBS692697-01Sonic Hedgehog (N-terminal)
hAP-0240Human Sonic Hedgehog (N-terminal)
MBS627095-01SHH (Sonic Hedgehog Protein, HHG-1, Sonic Hedgehog Protein N-product, Sonic Hedgehog Protein C-product)
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133323-HRPSHH (Sonic Hedgehog Protein, HHG-1, Sonic Hedgehog Protein N-product, Sonic Hedgehog Protein C-product) (HRP)
133323-BiotinSHH (Sonic Hedgehog Protein, HHG-1, Sonic Hedgehog Protein N-product, Sonic Hedgehog Protein C-product) (Biotin)
133323-FITCSHH (Sonic Hedgehog Protein, HHG-1, Sonic Hedgehog Protein N-product, Sonic Hedgehog Protein C-product) (FITC)
133323-APCSHH (Sonic Hedgehog Protein, HHG-1, Sonic Hedgehog Protein N-product, Sonic Hedgehog Protein C-product) (APC)
MBS6133743-01SHH (Sonic Hedgehog Protein, HHG-1, Sonic Hedgehog Protein N-product, Sonic Hedgehog Protein C-product) (AP)

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