SCF-R

• Description:

  Stem cell factor receptor (CD117, the gene product of the c-kit proto-oncogene) and its ligand, stem cell factor, play essential roles in gametogenesis, melanogenesis and hematopoiesis. Stem cell factor receptor is a member of the type III subfamily of receptor tyrosine kinases (RTK) that also includes the receptors for M-CSF, Flt-3 and PDGF. It is expressed in hematopoietic progenitor cells, normal B and T cell progenitor cells, mast cells, germ cells, melanocytes, neurons, glial cells, placenta, kidney, lung and gut.

• Synonyms:

  KIT, PBT; SCFR; C-Kit; CD117

• NCBI Gene ID:

  3815

• UniProt:

  P10721

• Accession Number:

  NP_000213.1

• Accession Number mRNA:

  NM_000222.2

• Chromosomal Location:

  4q11-q12

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human SCF-R EC domain

• Clone:

  (#14G5)

• Applications:

  WB, N

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG1